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hollywood casino columbus ohio address Experimental postdoctoral positions of gene regulation in cancer immunology and cancer biology, the University of Texas M.
Anderson Cancer Center The laboratory of Dr.
Yiwen Chen invites applications for experimental postdoctoral positions in studying the gene regulation in cancer immunology and cancer biology.
Our group is actively collaborating with the world-class cancer immunologists and cancer biologists at MD Anderson.
The highly interdisciplinary and collaborative environment of our group provides unique career development opportunities for the postdoc trainees.
The postdoc can be under the joint supervision of Dr.
The city of Houston is the 4th largest city in US and ranks the 12th best US travel destination in 2014.
Requirement: Experimental Postdoc: Applicants should have a Ph.
Strong background in one or more of the following areas i RNA biochemistry, ii immunology, iii molecular biology, iv cancer biology, and v mammalian cell biology.
All applicants should have good spoken and written communication skills.
Yiwen Chen, jobchenlab gmail.
D e-mail: taniguchimpfi gmail.
A new postdoctoral position for a highly motivated individual is open in 2017 at the Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York State at the laboratory of Dr.
Our lab focuses on Cellular Immunotherapy for Cancer.
Strong support for career development and advancement after postdoctoral will be further provided with good performance.
Requirements are a Ph.
Knowledge in immune assays, FACS, cell culture, PCR, mice handling, cell transfections or molecular biology are points considered for evaluation.
Hands-on knowledge in Bioinformatics and microarray analysis software will be considered a plus but not necessary.
Interested candidates please send a CV or personal summary to : Dr.
Our center has already Japanese nationals and the principal investigator speaks Japanese, so a smooth transition is expected.
The laboratory is interested into the mechanisms driving changes in the control of heterochromatin organization during the senescence process and how this impacts gene expression.
The successful candidate will work in close collaboration with the groups of Giacomo Cavalli and Evi Soutoglou to tackle this important question.
The Institute of Human Genetics is located in Montpellier, France.
This institute is one of the most renowned in France.
Montpellier is located in the south, on the Mediterranean border and is ~3 hours away from Paris with the high speed train.
Qualifications The candidate must hold a PhD degree or equivalent.
A good knowledge in molecular biology and chromatin biochemistry is desirable.
Experience in handling large datasets would be a plus.
Excellent communication skills are essential.
Salary Successful candidates will be offered competitive salary commensurate with experience and accomplishments.
Application details Please apply by sending your CV and a motivation letter stating your research and career interests, together with the name of references to: Jerome Dejardin - jerome.
The lab currently studies energy sensing and metabolism in cancer see our publications, Nature Cell Biology 2016; Nature Cell Biology 2015; Cancer Research.
The lab is well funded to support various projects related to the research topics described above.
Experience in using Mass Spectrometry-related technologies to study metabolism is highly desirable.
A track record of excellent first author publication during PhD training is essential.
MD Anderson is the number one cancer center in cancer care in the United States by the U.
It ranks 1st in the number of awarded grants from National Cancer Institute.
Houston is the 4th largest city in the United States with relatively low living cost and no state or city income tax.
The interested candidates should send a CV to bgan mdanderson.
Applicants should have a Ph.
Applicants should send 1 a cover letter with a description of past research experience, 2 CV, 3 a statement of research interests and career goals, and 4 contact information of 3 references to Dr.
Yohei Kirino at Yohei.
Computational Medicine Center Department of Biochemistry and Molecular Biology Sidney Kimmel Medical College Thomas Jefferson University Email: Yohei.
Kamaludin AA et al 2017 Hum.
Nakamura A et al 2017 J.
Rodrigues M et al 2016 Sci.
Echigoya Y et al 2015 Mol.
Pandey SN et al 2014 Mol.
Aoki Y et al 2013 Hum.
Aoki Y et al 2012 Proc.
Taniguchi M et al 2011 Nature, 478:127—131.
The Fellows will have an opportunity to study the molecular mechanism of chromatin and non-coding RNAs in epigenetic gene silencing, cellular dormancy and metabolism.
The ideal candidates have productive Ph.
The Fellow will lead a collaborative project involving several labs at the Massachusetts General Hospital and Harvard Medical School.
The laboratory is grounded in a strong basic research focus and is working closely with the clinical researchers at the MGH Cancer Center.
Please email a one-page cover letter, CV, and contact information of three referees to: mmotamedi hms.
Massachusetts General Hospital Cancer Center Harvard Medical School Room 7.
We seek to understand the genetic and epigenetic basis of organ regeneration and tumorigenesis.
We utilize genetic, live imaging, cell biological and next generation sequencing technologies to study the behavior of tissues at single cell level.
We offer an inspiring intellectual, collaborative and multidisciplinary research environment to support your career goals and provide access to state-of-the-art facilities.
Candidates with back ground knowledge and hands-on experience in transcriptional regulation and bioinformatics skills are particularly welcome.
Prior experience in stem cells, chromatin biology and bioinformatics is advantageous.
Purushothama Rao Tata purushothamarao.
The positions are available from February 1, 2017.
We are particularly interested in the pathogenesis and targeted therapy of lung and kidney cancers.
Applicants should hold a Ph.
Full applications including curriculum vitae and a list of three references should be submitted through chenge1 mskcc.
Journal of Immunology, 196 12 :4977-86, 2016 featured article.
Mingyi Xie Assistant Professor, Department of Biochemistry and Molecular Biology, Cancer Center, School of Medicine, University of Florida Function and biogenesis of alternatively-processed microRNAs Integrator complex-mediated RNA processing and gene regulation Applicants should submit the following to mingyi.
Mingyi Xie was trained in the laboratory of Dr.
Mammalian m7G-capped precursor miRNAs are generated from RNA polymerase Pol II transcription initiation sites.
Whereas the nuclear-cytoplasmic export of capped pre-miRNAs is mediated by Exportin-1 Xie et al.
Such research will allow the design of therapies for related oncogenic herpesviruses and cancers.
University of Florida UF is a vibrant intellectual community with many cross-disciplinery interactions.
UF is ranked as top-50 world university and top-15 public university in the United States by USNEWS.
Gainesville is a delightful and family-friendly city that is 1.
Future projects in the lab engage the use of biochemistry, molecular biology and genetic approaches, cell culture techniques and potentially!
Wei is looking for self-motivated individuals to become involved in the challenging and rewarding environment of the laboratory.
D Associate Professor Dept.
The ideal applicant will have PhD in Cell Biology, Genetics, or related field and experience with animal models of kidney injury surgical and nephrotoxicmouse husbandry, monitoring kidney function serum creatinine and BUN measurementsmolecular biology PCR, plasmid construction and transfectiontissue culture, biochemistry immunoblotting and immunostaining and data analysis.
A significant portion of the research conducted in our group focuses on understanding the role of cell cycle arrest in the progression of fibrosis in the kidney, leading to chronic kidney disease.
Other projects include: Delineating the mechanism and therapeutic potential of autophagy activation in the regulation of immune processes in AKI; and examining if mitochondrial dynamics proteins, such as mitofusins, modulate autophagic flux in AKI.
There are multiple opportunities to lead projects and to participate in ongoing studies.
The projected start date is flexible with intent to!
Qualified applicants should submit a cover letter describing previous research experience as well as current interests, curriculum vitae and contact details of three references to Craig Brooks, Ph.
The laboratory is located in a new building providing interactive environment and various state-of-the-art research facilities.
We are looking for highly motivated candidates with an interest in gene regulation in yeast and mammalian cells.
The proposed projects will utilize state-of-the-art biochemistry and structural approaches combined with the functional genome-wide analysis to understand how transcription factors and chromatin modifiers regulate transcription of protein-coding and non-coding genesis in yeast and mammalian cells.
The structural study will be done as a part of existing productive collaboration with Jonathan Grimes laboratory at STRUBi Oxford.
Candidates trained in protein purification, RNA analysis, and mammalian cell culture are encouraged to apply.
Basic knowledge of bioinformatics is beneficial.
Applicants should have or will shortly obtain a PhD and are expected to be highly motivated, with excellent critical thinking skills and with good communication skills and have the ability to work as part of a team.
Interested applicant should contact Dr Lidia Vasiljeva directly: Dr.
Professor of Pharmacology and Experimental Therapeutics and Neurology Boston University School of Medicine Boston, MA 02118, U.
Asai H, et al.
Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Stern RA, et al.
Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy.
To gain further insights into such regenerative responses, such responses are also interrogated during kidney development.
In addition, the laboratory will leverage on the world-class human induced Pluripotent Stem Cell iPS core facilities of RMI to establish in-vitro human nephrogenesis systems for kidney disease modeling and investigation of human renal repair responses.
The ideal candidate will have outstanding molecular and cell biology training with experience of the above genetic technologies.
The recently published paper illustrates the type of scientific work the laboratory conducts: Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney.
Kumar S et al.
Cell Reports 2015 August 25, 12: 1325 - 38.
TRIF-independent branch of TLR3 signaling.
Antiviral innate immunity disturbs podocyte cell function.
PACT 500 Los Angeles, CA 90048 Email: michifumiyamashita gmail.
In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche.
Joji Fujisaki, MD PhD Assistant Professor Division of Hematology and Oncology Department of Pediatrics Director of In Vivo Imaging Columbia Center for Translational Immunology Columbia University College of Physicians and Surgeons POSTDOCTORAL POSITION AVAILABLE A postdoctoral position is open in the area of molecular pathogenesis of age-related diseases at Northwestern University School of Medicine in Chicago, USA.
Applicants may send a brief summary of past accomplishment and curriculum vitae by email to Professor Jane Wu jane-wu northwestern.
Our laboratory aims to examine RNA-helicases and their associated non-coding RNAs in nuclear architecture and transcription, post-transcriptional and post-translational regulation, and cell-fate determining metabolic switches underlying the development and effector functions of immune cells and their contribution to immune related diseases.
Experience in working with mice, flow cytometry and molecular biology in RNA and protein assays is required.
Candidate should have demonstrated ability to work independently, attention to details, be dedicated, and self-motivated.
Please send a CV, statement of past research experiences, and contact information of three referees to Wendy Huang at wendyjmhuang ucsd.
D EMAIL: wendyjmhuang ucsd.
EDU The Center for Immunotherapy CFI at Roswell Park Cancer Institute is one of the largest cancer immunotherapy research centers under the leadership of Kunle Odunsi.
Post-doctoral research position is available in my laboratory, which focuses on tumor microenvironment, chemokines and T cell homing, and check point inhibition in ovarian cancer.
The candidate should have a Ph.
The research focus is highly translational with pre-clinical work that leads up to novel clinical trials.
The candidate must be able to work independently, with excellent interpersonal and manuscript writing skills.
Academic activities, such as conference attendance and mentoring are included.
J Bone Miner Res.
Epub 2015 Jul 28.
Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y.
Proc Natl Acad Sci U S A.
Assistant Professor Department of Pediatrics The University of Texas Medical School at Houston 6431 Fannin St, Houston, TX 77030 Yoshihiro.
Curr Mol Med 15 2 :138-45.
Molecular Psychiatry 18 7 :740-2.
Neuroscience Research 71 3 :289-93.
Nature Immunology 9 1 :34-41.
Assistant Professor Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine E-mail: skano2 jhmi.
Chan School of Public Health, Brigham and Women's Hospital BWHand Harvard Medical School, in Boston, MA, USA.
Salary can be offered if a candidate has specific skills and expertise.
A position may be a research scientist or postdoctoral fellow.
A new lab member will be affiliated with Division of MPE Molecular Pathological Epidemiology at BWH.
Candidates in other areas can be considered; other areas include epidemiology, biostatistics, molecular biology, immunology, microbiology, and clinical medicine.
Candidates with funding support will be highly considered, but candidates without funding will also be considered.
My laboratory is The "Molecular Pathological Epidemiology" MPE Laboratory, which is a very unique, interdisciplinary multi-institutional laboratory.
I established an integrative science of MPE Ogino et al.
J Natl Cancer Inst 2010; Ogino et al.
Nat Rev Clin Oncol 2011; Field et al.
I founded the International MPE Meeting Series, and the 3rd International Molecular Pathological Epidemiology MPE Meeting in May 2016 concluded as a resounding success.
In terms of disease areas, my lab has been working on colorectal cancer, pancreatic cancer, and gastrointestinal neuroendocrine tumors.
We have been utilizing resources of the Nurses' Health Study following 121,700 women since 1976the Health Professionals Follow-up Study following 51,500 men since 1986GECCO Genetics and Epidemiology of Colorectal Cancer ConsortiumAlliance trials, and other resources.
Please pass this information to anyone who may be interested.
Please note that I may not reply to all inquiries.
Selected original publications: X Liao et al.
NEJM 2012; R Nishihara et al.
NEJM 2013; AT Chan et al.
NEJM 2007; E Barry et al.
Nature 2013; R Straussman et al.
Nature 2012; M Giannakis et al.
Nat Genet 2014; R Nishihara et al.
JAMA 2013; T Morikawa et al.
JAMA 2011; AT Chan et al.
JAMA 2009; K Nosho et al.
Gastroenterology 2009; K Nosho et al.
J Pathol 2010; S Fink et al.
Sci Transl Med 2014; ZR Qian et al.
J Clin Oncol 2013; A Kostic et al.
Genome Res 2012; M Song et al.
JNCI 2015; K Inamura et al.
JNCI 2014; P Lochhead et al.
JNCI 2013; S Ogino et al.
JNCI 2013; A Kuchiba et al.
JNCI 2012; M Song et al.
Gut 2016; M Yamauchi et al.
Gut 2012; K Mima et al.
Cancer Immunol Res 2015; K Mima et al.
JAMA Oncol 2015; K Inamura et al.
JNCI 2016; K Mima et al.
Gut 2016; M Song et al.
JAMA Oncol 2016; M Giannakis et al.
Cell Reports 2016, Y Cao et al.
Gastroenterology onlineetc.
JNCI 2010; S Ogino et al.
Nat Rev Clin Oncol 2011; A Field et al.
HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway.
Kagoya Y et al.
BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.
Butler MO and Hirano N.
Human cell-based artificial antigen-presenting cells for cancer immunotherapy.
Butler MO et al.
Establishment of antitumor memory in humans using in vitro-educated CD8+ T cells.
Computational Medicine Center Department of Biochemistry and Molecular Biology Sidney Kimmel Medical College Thomas Jefferson University 1020 Locust Street, Jefferson Alumni Hall M77, Philadelphia, PA 19107, USA Tel: +1-215-503-8648 Email: Yohei.
A highly motivated postdoctoral scholar will work on NIH-funded research projects to study the central regulation of energy homeostasis and cardiovascular function.
To accomplish this, a combination of cutting-edge tools will be employed, including in vivo Cre-loxP technology, optogenetics and chemogenetics, functional neuroanatomy, neurophysiology, biochemistry and molecular biology.
Applicants should have a Ph.
Prior working experience with animal models is highly desirable.
Preference will be given to those who have expertise in neuroanatomy, small animal surgery, metabolism and cardiovascular research.
To Apply: Interested candidates should submit their current curriculum vitae, letter of interest, and contact information for 3 references to Dr.
Huxing Cui by e-mail at: huxing-cui uiowa.
All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.
A postdoctoral position is available with a flexible start date in the field of cancer epigenetics in the Deshpande Lab at the Sanford Burnham Prebys Medical Discovery Institute SBP in La Jolla, California.
The Deshpande Lab is interested in cancer epigenetics with a core focus on hematological malignancies using mouse models see Deshpande et al.
The lab also has a strong interest in normal hematopoietic stem cell biology.
The candidate will be involved in the study of normal and cancerous stem cells using genomic, epigenomic and biochemical methods, high-throughput small molecule inhibitor screens and CRISPR-Cas9 mediated genome and epigenome editing.
SBP is an NCI-designated Cancer Center and is known for its world-class capabilities in cancer and stem cell research and drug discovery technologies.
SBP is located on the scenic Torrey Pines Mesa and has collaborative ties to several adjacent world-renowned research institutions such as the Salk Institute, Scripps and the University of California San Diego as well as several leading pharmaceutical companies.
Requirements Highly motivated candidates with a recent Ph.
Experience and expertise in cell and molecular biology multi-parameter flow cytometry, chromatin immunoprecipitation, cell culture is highly desired.
Basic knowledge of computational data analysis is a big plus but not a must.
We are seeking collaborative individuals who are detail oriented, with excellent communication and data organization skills.
Candidates must have a demonstrated ability to successfully spearhead a research project as evidenced by first author publications in reputable and high impact journals published or submitted.
Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for 3 letters of reference to Dr.
Ani Deshpande adeshpande SBPdiscovery.
Patrick Osei-Owusu, in the Department of Pharmacology and Physiology at Drexel University College of Medicine in Philadelphia, PA.
A Qualified applicants should have a Ph.
The applicant should be independent and self-motivated, with excellent verbal and written communication skills.
The successful applicant will work on studies aim at unraveling the pathological mechanisms of high vascular tone and blood pressure disorders associated with pregnancy complications and spinal cord injury.
The project employs a combination of advanced and state-of-the-art techniques in integrated physiology, including mouse genetics, the development of lentiviral constructs for gene expression in primary cells, small animal echocardiography and Doppler ultrasound imaging, ex vivo vessel studies, calcium imaging, renal hemodynamics and blood pressure studies in rodent disease models using radiotelemetry, and signal transduction assays in primary and cultured cells.
Salary and benefits are commensurate with experience and institution guidelines.
To apply for this position, send CV and contact information of three references to Dr.
Patrick Osei-Owusu at patrick.
We are looking for a creative, accomplished and highly motivated applicant who is interested in research involving noncoding RNA mediated epigenetic mechanisms and the role of these processes in cancer.
In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche.
Assistant Professor Children's Nutrition Research Center Department of Pediatrics Baylor College of Medicine Email: fukuda bcm.
Kaneko K, Xu P, Cordonier EL, Chen SS, Ng A, Xu Y, Morozov A, Fukuda, M.
Cell Reports, In press.
Fukuda M, Williams KW, Gautron L and Elmquist JK.
Our work takes a multi-disciplinary in vivo approach to study the development and function of inhibitory interneurons in epilepsy, combining molecular, anatomical, electrophysiological, imaging and behavior methodologies using mouse models and human induced pluripotent stem cells.
The lab is currently funded by multiple NIH and private foundation grants to support these projects.
Competitive applicants should have at least one high-quality, first-author publication.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.
Curriculum Vitae - Your most recently updated C.
Statement of Research - Describe prior experience, future goals, and address how you think you can contribute to the overall research direction of the Hunt laboratory 4.
The Neppl laboratory is focused on the molecular regulation of skeletal muscle homeostasis in health and disease.
Our overarching goal is to understand how ncRNAs control the essential processes of myogenesis and hypertrophic growth, and how perturbations in these processes may lead to a disease state resulting in muscle atrophy.
Using traditional biochemical and molecular biology techniques, in vivo and in vitro model systems, as well as next generation RNA sequencing, we seek to discover and understand the biological roles these ncRNAs play in the maintenance of lean muscle mass.
Qualifications The ideal candidate will have an M.
Excellent oral and written communication skills in English are essential.
Interested candidates should provide: 1 your CV 2 A brief letter detailing your interest in the lab and relevant past research experience 3 The contact information for three references who can comment on your research Application materials and any questions regarding the position should be sent to: Dr.
TRIF-independent branch of TLR3 signaling.
Antiviral innate immunity disturbs podocyte cell function.
PACT 500 Los Angeles, CA 90048 Email: Michifumi.
Assistant Professor of Biochemistry and Chemistry Duke University Medical Center 307 Research Drive, Rm 233 Nanaline H.
Duke Bldg, Durham, NC, 27710, USA Tel: 919 684-8848 Email: ken.
The Department of Cardiology at MD Anderson was founded in 2000 as the first onco-cardiology unit in the world to provide comprehensive cardiac care to patients with cancer.
The vision of the Department of Cardiology is to be the model of onco-cardiology or cardio-oncology units throughout the world.
Approximately 75% of cancer survivors have some form of chronic health problem.
Cardiovascular diseases CVDs are the leading cause of morbidity and mortality in this population, particularly after recurrent or second malignancy.
The risk of CVD in cancer survivors is 8 times higher than that of the general population.
The relative risks of coronary artery disease and heart failure in cancer survivors are 10 times and 15 times higher, respectively, than their siblings without cancer.
Cancer treatments, including chemotherapy and radiation, can lead to both short- and long-term cardiovascular complications.
Evidence of subclinical cardiac and vascular damage was observed in more than 50% of survivors 5 to 10 years after chemotherapy.
Although it has been well recognized clinically, it is not understood how various forms of cancer therapy negatively affect cardiac as well as vascular functions.
Therefore, our visions are to reassess the effect of cancer and chemotherapy treat!
These studies will be especially critical to better understand cardiovascular disease in cancer survivors which is a major cancer-related morbidity.
The reorganized cardiovascular research group at MD Anderson that integrates the seemingly diverse areas of cancer biology, chemotherapy-mediated cardiac toxicity, and small molecule development with our research on both extra- and intra-cellular signal transduction pathways with technical expertise in confocal microscopy, cardio-vascular pathophysiology, and molecular imaging will be a highly competitive research program second to none.
Our laboratories offer a wealth of technical capabilities including cardiovascular pathophysiology, confocal microscopy, proteomics, and analysis of signal transduction pathways including kinase and transcriptional activity.
Department of Cardiology at UT MD Anderson Cancer Center enjoys an interactive and collaborative environment ideal for scientific discovery.
We believe and always emphasize that forming of effective team is an intermediate goal towards performing good science and sustainable results.
Based on this concept, we offer multi-disciplinary training opportunities including a weekly seminar series, journal clubs, and other career-development activities, such as grant writing and funding in cutting-edge cardiovascular and oncology research in our center.
Please send a statement of research interests, curriculum vitae, and three letters of reference to: Jun-ichi Abe, MD, PhD, FAHA Professor Department of Cardiology Division of Internal Medicine University of Texas MD Anderson Cancer Center 2121 W Holcombe Blvd.
IBT8 803e Houston, TX 77030 713-745-2802 TEL 713-745-2816 FAX E-mail: jabe mdanderson.
Professor, Department of Pharmacology and Experimental Therapeutics and Neurology Boston University School of Medicine Boston, MA 02118, U.
Asai H, et al.
Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Stern RA, et al.
Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy.
Kaur M, Izumi K, Wilkens AB, Chatfield KC, Spinner NB, Conlin LK, Zhang Z, Krantz ID.
In press; Inoue et al.
A post-doctoral fellow position is available in the laboratory of Dr.
Muge Kuyumcu-Martinez at University of Texas Medical Branch to study the regulation of alternative splicing networks by RNA binding proteins in normal and diseased hearts.
We utilize inter-disciplinary approaches that combine mouse genetics, cell biology, genome editing, biochemistry, and genome-wide analyses e.
RNA-seq and CLIP-Seq to investigate molecular mechanisms that dictate splicing decisions in the heart.
We are looking for highly motivated, bright and enthusiastic applicants with a background in RNA biology, heart development or cardiac physiology.
The candidate should be to able to work as a team member, learn new skills rapidly, and have excellent communication skills.
Please click on the link below to find our recent publications in Cell Reports and Scientific Reports.
UTMB interacts and collaborates with the following institutes and medical schools in the Texas Medical Center including Baylor College of Medicine, Texas Heart Institute, Rice University, MD Anderson Cancer Center, University of Texas Medical School, and Methodist Research Institute.
UTMB is located in the Galveston island, which is very affordable and fun to live.
Water activities including sailing and surfing are available throughout the year due to the warm climate.
In addition, Galveston is only 50 miles away from Houston, which is the fourth biggest city in the US.
If you are interested, please e-mail me your curriculum vitae, statement of career interests 1 paragraph longand contact information for three references.
Muge Kuyumcu-Martinez, PhD Assistant Professor Department of Biochemistry and Molecular Biology The University of Texas Medical Branch Galveston, TX 77555 E-mail: nmmartin utmb.
The lab uses mouse genetics, biochemical, cellular and molecular biology tools to dissect the roles of transcription factors and signaling molecules in vivo.
Our long-term goal is to understand how defects in developmental pathways could lead to diseases such as lymphedema and valvular dysfunction.
We are also interested in understanding the comorbidities of lymphedema such as fibrosis.
Please check our recent publications: Srinivasan et al 2011 Genes Dev.
Oct 15;25 20 :2187-97; Srinivasan et al 2014 Genes Dev.
Oct 1;28 19 :2175-87; Geng et al 2016 Dev Biol.
OMRF is an independent, not-for-profit, biomedical research institute in Oklahoma City.
OMRF has been selected as one of the best research institutions for post-docs from 2011 to 2013 in the USA by The Scientist journal.
Oklahoma City metropolitan area offers affordable housing, excellent public schools and diverse entertainment opportunities.
The ideal candidate will be a recent graduate, have a good record of publications, interested in Developmental Biology and Disease Modeling and posses excellent communication and laboratory skills.
Special Instructions to Applicants: Please send a curriculum vitae and summary of research interests to: Sathish Srinivasan Ph.
Scientists within the neuroscience department have strong expertise in neurogenetics, neuropathology, animal disease modeling, neuroinflammation, and experimental therapeutics.
Our recent articles related with the current projects 1 J Neurosci.
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis.
Salary will be still matched to the NIH NRSA stipend scale.
Application process - Please email the following items in "one" PDF file to kim.
Cover letter, including brief statement of achievements and future research interest 2.
CV, including detail technical expertise and PubMed links for the published articles 3.
Senior Associate Consultant Assistant Professor Department of Neuroscience Mayo Clinic College of Medicine 4500 San Pablo Road Jacksonville, FL 32224 PS If preferred, onsite interview is available during the following conferences.
Chan School of Public Health is looking for an outstanding postdoctoral fellow.
Emerging studies indicate that metabolic reprogramming critically controls macrophage activation, and a variety of projects are available in the lab addressing various aspects of such control, including the metabolic basis of Nlrp3 inflammasome activation; metabolic crosstalk between tumor associated macrophages and tumor cells; and metabolic influences on chromatin-mediated control of macrophage activation and memory.
Candidates should be skilled in cell biology, molecular biology, and basic mouse work.
Candidates must have a Ph.
Please submit application, including a cover letter, CV and names and contact information of at least 3 references to: Tiffany Horng, Ph.
Associate Professor Department of Genetics and Complex Diseases Harvard School of Public Health 655 Huntington Ave, II-115 Boston, MA 02115 thorng hsph.
The ideal candidate could be finishing up graduate studies or completed graduate studies with no more than one year of post-PhD research experience.
Experience in molecular biology including in-depth understanding of molecular cloning, DNA, RNA and protein work and extensive cell culture is required.
Some experience in mouse genetics is preferable.
Background in cancer biochemistry, metabolism, signaling and genetics will be considered favorably and interest in the above fields is necessary.
Candidates with an interest in the position should send their CV and contact information for 3 references to: Biplab.
Using genetically engineered mouse models and human tissue, the Dasgupta lab has been engaged in cutting-edge research to understand neural stem cell metabolism, genetic and metabolic uniqueness of glioblastoma a type of brain tumor subtypes, energy and nutrient sensing signaling pathways in cancer versus normal cellular counterparts and the built-in metabolic vulnerabilities of human cancer cells.
We are also deeply interested to understand the mechanisms by which non-genetic factors regulate the incidence and penetrance of human cancer.
We have published our work in highly visible journals including Nature Communications, PNAS, Cancer Cell, and Cancer Research.
Our current study on a novel mechanism of tumorigenesis in pediatric brain tumors will be published soon in Neuro-Oncology, and studies on the bioenergetic regulation of brain tumors is under review in Nature Medicine.
Click on the PubMed link to learn more.
Ongoing studies are focusing on death receptor-mediated cancer cell death and reversal of tumor resistance to TNF-related apoptosis-inducing ligand TRAIL or death receptor agonistic antibodies by small molecules.
Excellent written and interpersonal communication skills are required.
Bioinformatics skills are a plus.
The position is funded for 1 year and renewable upon satisfactory evaluation.
Minimum Requirement: Recent PhD or equivalent in biomedical sciences Excellent verbal and written communication skills.
Wang, MD, PhD Assistant professor Department of Medical Oncology City of Hope Comprehensive Cancer Center 1500 E Duarte Road Duarte, CA 91010 edw.
This position will be responsible for conducting studies on novel genetic mouse model developed in our laboratory to study lipid signaling hollywood casino columbus ohio address in colonic tumorigenesis.
The duties of this position include: 1.
To conduct study design, experimentation, data collection, and data analysis.
To prepare manuscript and present data at national annual meetings.
Qualifications: To be considered for this position you must have a Ph.
D or equivalent doctorate degree.
Interested applicants should email a CV and research letter of interest to ishureiqi mdanderson.
It ranks 1st in the number of awarded grants from National Cancer Institute.
It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world's largest biomedical center.
Houston is the 4th largest city in the United States with relatively low living cost and no state or city income tax.
New postdoctoral positions are open in a cancer research laboratory located within The University of Texas MD Anderson Cancer Center.
The lab currently studies energy sensing and metabolism in cancer see our publications, Nature Cell Biology 2016; Nature Cell Biology 2015; Cancer Research.
The lab is well funded to support various projects related to the research topics described above.
Experience in using Mass Spectrometry-related technologies to study metabolism is highly desirable.
A track record of excellent first author publication during PhD training is essential.
MD Anderson is the number one cancer center in cancer care in the United States by the U.
It ranks 1st in the number of awarded grants from National Cancer Institute.
Houston is the 4th largest city in the United States with relatively low living cost and no state or city income tax.
The interested candidates should send a CV to bgan mdanderson.
PNAS, 2007; Matsuzaki J, et al.
Cancer Immunol Immunother, 2008; Matsuzaki J, et al.
PNAS, 2007; Odunsi K, Matsuzaki J, et al.
PNAS, 2012; Odunsi K, Matsuzaki J, Cancer Immunol Res, 2013; Matsuzaki J, et al.
Cancer Immunol Res, 2014; Matsuzaki J, et al.
We seek to understand the genetic and epigenetic basis of organ regeneration and tumorigenesis.
We offer an inspiring intellectual, collaborative and multidisciplinary research environment to support your career goals and will have access to state-of-the-art facilities.
Prior experience in stem cells, chromatin biology is advantageous but not necessary.
Purushothama Rao Tata purushothamarao.
The positions are available from October 1, 2016.
Chan School of Public Health, Brigham and Women's Hospital BWHand Harvard Medical School, in Boston, MA, USA.
Salary can be offered if a candidate has specific skills and expertise.
A position may be a research scientist or postdoctoral fellow.
A new lab member will be affiliated with Division of MPE Molecular Pathological Epidemiology at BWH.
Candidates in other areas can be considered; other areas include epidemiology, biostatistics, molecular biology, immunology, microbiology, and clinical medicine.
Candidates with funding support will be highly considered, but candidates without funding will also be considered.
My laboratory is The "Molecular Pathological Epidemiology" MPE Laboratory, which is a very unique, interdisciplinary multi-institutional laboratory.
I established an integrative science of MPE Ogino et al.
J Natl Cancer Inst 2010; Ogino et al.
Nat Rev Clin Oncol 2011; Field et al.
JAMA 2013; etcand founded the International MPE Meeting Series.
I recently hosted The 3rd International Molecular Pathological Epidemiology MPE Meeting on May 12-13, 2016, and it concluded as a resounding success.
Indeed, I have been making history of MPE.
In terms of disease areas, my lab has been working on colorectal cancer, pancreatic cancer, and gastrointestinal neuroendocrine tumors.
We have hollywood casino columbus ohio address utilizing resources of the Nurses' Health Study following 121,700 women since 1976the Health Professionals Follow-up Study following 51,500 men since 1986GECCO Genetics and Epidemiology of Colorectal Cancer ConsortiumAlliance trials, and other resources.
For more information, please visit these links.
Please pass this information to anyone who may be interested.
Please note that I may not reply to all inquiries.
Selected original publications: X Liao et al.
NEJM 2012; R Nishihara et al.
NEJM 2013; AT Chan et al.
NEJM 2007; E Barry et al.
Nature 2013; R Straussman et al.
Nature 2012; M Giannakis et al.
Nat Genet 2014; R Nishihara et al.
JAMA 2013; T Morikawa et al.
JAMA 2011; AT Chan et al.
JAMA 2009; K Nosho et al.
Gastroenterology 2009; K Nosho et al.
J Pathol 2010; S Fink et al.
Sci Transl Med 2014; ZR Qian et al.
J Clin Oncol 2013; A Kostic et al.
Genome Res 2012; M Song et al.
JNCI 2015; K Inamura et al.
JNCI 2014; P Lochhead et al.
JNCI 2013; S Ogino et al.
JNCI 2013; A Kuchiba et al.
JNCI 2012; M Song et al.
Gut 2016; M Yamauchi et al.
Gut 2012; K Mima et al.
Cancer Immunol Res 2015; K Mima et al.
JAMA Oncol 2015; K Inamura et al.
JNCI 2016; K Mima et al.
Gut 2016; M Song et al.
JAMA Oncol 2016; M Giannakis et al.
Cell Reports 2016, etc.
JNCI 2010; S Ogino et al.
Nat Rev Clin Oncol 2011; A Field et al.
Nima Sharifi at the Cleveland Clinic Lerner Research Institute in the Department of Cancer Biology.
Our laboratory is focused on molecular mechanisms of androgen synthesis and androgen receptor AR gain-of-function that lead to resistance to hormonal therapy.
Specific areas include: 1 Metabolic and genetic changes required for androgen synthesis 2 Clinical validation in patients and clinical trials utilizing innovative approaches 3 Animal models of advanced prostate cancer for translational and therapeutic studies 4 Identifying targets for the development of new pharmacologic therapies We recently discovered that abiraterone works by conversion to a more active steroidal metabolite Li, et al.
We are currently working toward defining the relationship between metabolite generation and treatment response in patients and identifying new chemical entities that are determinants of treatment response.
We also discovered the first example of a gain-of-function in a steroid-synthesizing enzyme that enables prostate cancer resistance to hormonal therapy Chang, et al.
We are pursuing similar mechanisms and developing new treatment modalities based on these discoveries.
can you make money at casinos, we discovered that prostate cancer becomes resistant to hormonal therapy by the synthesis of dihydrotestosterone through a pathway that circumvents testosterone, instead requiring 5α-androstanedione, a previously underappreciated intermediate metabolite.
This metabolic pathway occurs in patient tumors Chang, et al.
Proc Natl Acad Sci USA.
The position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development and clinical trials.
Candidates must have proficiency in verbal and written English.
Candidates with an interest in the position should send their CV and contact information for 3 references to: Nima Sharifi, M.
Kendrick Family Chair for Prostate Cancer Research sharifn ccf.
Assistant Professor Department of Pediatric, Infectious Diseases and Immunology Department of Biomedical Science Cedars-Sinai Medical Center E-mail: kenichi.
Postdoctoral positions are available in the laboratory of Dr.
Linda Buck to investigate mechanisms and neural circuits that underlie odor perception or instinctive odor responses in mice.
Another will focus on mechanisms and neural circuits underlying the effects of odors on fear or appetite.
The lab is interested in the normal functioning of these circuits as well as how they may be altered in disease states or during aging.
The Buck lab uses a variety of traditional and cutting edge technologies to study the nervous system.
These include transcriptomics, molecular biology, genetics, behavioral analysis, chemogenetics, and optogenetics.
Also see recent Buck lab publications: Hanchate et al 2015 Science and Kondoh et al 2016 Nature.
Buck is an Investigator of the Howard Hughes Medical Institute HHMI in the Basic Sciences Division at Fred Hutchinson Cancer Center FredHutch in Seattle and also an Affiliate Professor of Physiology and Biophysics at the University of Washington.
FredHutch has been home to three Nobel Laureates, including Dr.
Buck Nobel Prize in Physiology or Medicine, 2004.
Its Basic Sciences Division is a vibrant community of basic scientists working in diverse research areas, including molecular evolution, chromatin, cell biology, and neurobiology.
Applicants should be enthusiastic about science hollywood casino columbus ohio address have a background in neuroscience, molecular biology, or cell biology.
Interested applicants should send their CV, a short description of current and future research interests, and the names and email addresses of three references to Linda Buck at lbuck fredhutch.
Post-doctoral Position Available A Post-doctoral position is immediately available in the laboratory of Dr.
Golam Mohi at the State University of New York, Upstate Medical University to study the molecular and epigenetic mechanisms of myeloproliferative neoplasms and myeloid leukemia.
The project offers unique opportunity to utilize state-of-the-art techniques and genetically engineered mouse models to uncover the mechanisms involved in leukemogenesis.
Please see some of our recent publications- 1.
Blood 2016 Apr 14; Epub ahead of Print 2.
Leukemia 2015, 29 10 :2050-2061 3.
Stem Cells 2014, 32 7 :1878-1889 4.
Leukemia 2014, 28 8 :1627-1635 5.
Blood 2012, 119 15 :3539-3549 6.
Blood 2012, 119 16 :3779-3789.
Candidates should have a recent Ph.
Candidates must have a proven track record in research with first author publications in reputed journals.
Experience in flow cytometry, animal handling and hematopoiesis studies will be preferred.
Applicants should send a cover letter, curriculum vitae, a summary of research experience and the names and contact information e-mail and telephone numbers of three references to Dr.
Golam Mohi at mohim upstate.
WHA 6290 Syracuse, NY 13210, USA E-mail: mohim upstate.
Illinois at Chicago, Dept.
Curr Mol Med 15 2 :138-45.
Molecular Psychiatry 18 7 :740-2.
Neuroscience Research 71 3 :289-93.
Nature Immunology 9 1 :34-41.
Assistant Professor Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine E-mail: skano2 jhmi.
We are looking for highly motivated, independent, and talented individuals who want to investigate epigenetic mechanisms underlying the female bias in autoimmune disorders and immunological responses.
Applicants should hold a doctoral degree Ph.
Interested candidates should email their CV and cover letter, along with names and contact information of three references to Anguera vet.
Acute myeloid leukemia AML is the most common type of aggressive blood cancer in adults.
The standard treatment for AML has been developed in the early 1970s and, since then, very little progress has been made to improve the overall 5-year patient survival rate which is about 25%.
In this research project, we aim to identify chromatin factors that can potentially serve as novel targets for therapies in AML.
The project will require using recombinant lentiviruses, cell lines and tumor samples from patients.
A previous experience with cell culture is therefore desirable.
Mastering molecular biology techniques e.
Applications from students with different skills, but having shown adaptability, may be considered.
Our research group is located at the Institute for Molecular Biology and Tumour Research IMT of the University of Marburg.
The institute provides a state-of-the-art and international environment.
A strong interest in basic research and good communication skills in English are a prerequisite.
To find out more about the project, please, send a motivation letter, a CV and the names of, at least, one referee as a merged PDF file to Dr.
The lab investigates gene regulation by non-coding RNAs by employing a combination of biochemistry, cell and molecular biological methods, and genome wide approaches.
Candidates with research interests in chromatin biology, epigenetics, and long non- coding RNAs are encouraged to apply.
Candidates must have a strong background in RNA and protein biochemistry.
Candidates should have a PhD or equivalent degree or should be close to obtaining their doctoral degree.
Interested individuals should apply by submitting a cover letter stating the reason for their interest in the position, a CV including a list of publications, and the names and contact information for at least 3 references to ksarma wistar.
The Wistar Institute is an independent biomedical research institute founded in 1892 and is world renowned for its research in cancers and vaccine development.
It is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus.
Both the Wistar Institute and the University of Pennsylvania provide resources to conduct cutting edge collaborative research, outstanding intellectual environments and state-of-the-art facilities.
For more information about The Wistar Institute visit our website at www.
It is the policy of The Wistar Institute to provide equal employment opportunities to all individuals regardless of race, color, creed, religion, national origin, ancestry, sex, age, veteran status, disability, sexual orientation, gender identity, or on the basis of genetic information, or any other characteristic protected by federal, state, or local law, with respect to all terms and conditions of employment.
TRIF-independent branch of TLR3 signaling.
Antiviral innate immunity disturbs podocyte cell function.
PACT 500 Los Angeles, CA 90048 Email: michifumiyamashita gmail.
Candidates with demonstrable competence and proficiency in tissue culture, immunoprecipitation, immunofluorescence, and cloning will be considered.
Also, the position will be a Postdoctoral Scholar-Research Associate.
Salary is within the NIH training guideline.
It is a temporary, fixed-term; one year and renewable on the recommendation of the faculty mentor and at the discretion of the dean.
Please send a cover letter, CV, three reference letters to Dr.
Chengyu Liang at Chengyu.
Post-doctoral position in Cellular and Molecular Immunology Mucosal ImmunologyKeck School of Medicine, University of Southern California, Los Angeles, CA We are seeking a recent graduate and motivated individuals with PhD in Immunology to join our studies on mucosal immunology.
The applicants should have at least 1-2 immune related published articles and have recently graduated or expect to graduate soon.
Description A post-doctoral positions are available in my laboratory to study immunoregulatory pathways that control the innate and adaptive immune responses involved in the pathogenesis of allergic disease and asthma.
This position will be focused on defining molecular and cellular mechanisms, integrate cutting edge molecular technologies with traditional cell and molecular biology based approaches.
Please refer to our recent publication for further information Immunity.
March 2015 or J Allergy Clin Immunol.
We are seeking highly motivated and collaborative individuals capable of independent reasoning and excited about learning new technologies.
The candidates should have excellent writing and communication skills and familiar with techniques such as multi color flow cytometry, cell isolation, tissue culture, ELISA, RT-PCR, animal handling and preferably measuring airway hyperreactivity.
This job is open only for recent graduate applicants with PhD or applicants that expect to graduate from PhD program soon.
Applicants should have at least one or two immune related published articles preferably related to mucosal immunology and airway inflammation.
The laboratory is located in the recently built Norris Research Tower, Keck School of Medicine with full time access to excellent facilities in the department and the University.
Interested individuals should send their curriculum vitae, a brief description of their research interest, and the names of three references to: Omid Akbari, Ph.
The research interest of our laboratory lies in identifying new effective therapies to improve the outcome of children with brain tumors.
Our laboratory studies to understand the genetic and epigenetic mechanisms that promote cancer development and progression, and would accordingly reveal potential therapeutic targets.
We utilize animal model systems that faithfully recapitulate the biology and genetics of human brain tumors.
Our current projects focus on epigenetic targeting therapy for the treatment of pediatric brain cancer.
Specifically, it is our current intention to investigate the role of K27M H3F3A mutation on histone methylation and gene expression in brainstem gliomas.
Our laboratory is well funded from internal and exter!
Select publications include: Lerner RG, Grossauer S, Kadkhodaei B, Meyers I, Koeck K, Sidorov M, Hashizume R, Ozawa T, Berger MS, Nicolaides T, James CD, Petritsch C.
Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells.
Epub 2015 Nov 16.
Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan Hollywood casino columbus ohio address />EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.
Nature Neuroscience, 2015, Aug10.
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Nature Medicine, 2014 Dec;20 12 :1394-6.
Mueller S, Hashizume R, Yanh X, Kolkowitz I, Olow AK, Phillips J, Smimov I, Tom MW, Prados MD, James CD, Berger MS, Gupta N, Haas-Kogan DA.
Targeting Wee1 for the treatment of pediatric high-grade gliomas.
Neuro Oncology, 2014 Mar; 16 3 :352-60.
Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, Gupta N, Mueller S, James CD, Jenkins R, Sakaria J, Zhang Z.
We are seeking a qualified postdoctoral fellow with an interest in chromatin biology, genetic and epigenetic mechanism of cancer, and translational research for preclinical therapeutics in brain tumor animal models.
The fellow will design and perform experiments using a variety of model systems mouse, rats, tissue culture and techniques molecular, biochemistry, epigenetics, genetic, histology, and genomics.
Postdoctoral fellow in the lab involves close interactions both within the lab and with collaborating groups at the Northwestern University Feinberg School of Medicine.
A major goal of our lab is to mentor and train fellows for future careers in academics and industry.
To apply, please email a statement about your interest in our lab, your career goals, objectives, and a CV that includes three references to Dr.
Associate Biologist, Renal Division, Brigham and Women's Hospital Instructor, Harvard Medical School morizanr da2.
Project Title: The role of vascular exosome in mediating cardiovascular pathophysiology.
Position Type: Postdoctoral Position at an Academic Institution My laboratory is looking for a post-doctoral fellow commitment for 2 years or more to conduct both in vitro and in vivo research experiments focused on the signal transduction mechanisms of vascular disease development 1.
Vascular exosome and 2.
Cutting-edge cell biological and biochemical approaches, genetic mouse models, large animal models and human tissue specimens will be employed during the training period.
Applicants must have a Ph.
Two positions are currently available with full financial support NIH standard up to 3-4 years.
Victor Rizzo, PhD Professor of Medicine Temple University School of Medicine Department of Anatomy and Cell Biology Independence Blue Cross Cardiovascular Research Center 3500 N.
Our group studies how injured tissues heal, and in some cases, how injured tissues regenerate without a scar.
We have innovated new methods for studying these processes in mice and humans, and discovered cellular, molecular, and genetic mechanisms governing inflammation, wound healing, and tissue regeneration.
Based on our findings, we have several active clinical trials testing our conclusions in the clinic.
As a practicing dermatologist, I try to use clinical observations to drive basic science discovery.
An overarching goal of our work is to identify novel therapeutic strategies to improve healing with or without scars in humans.
We are seeking a qualified postdoctoral fellow with an interest in stem cells, inflammation, tissue regeneration, and regenerative medicine.
The fellow will design and perform experiments using a variety of model systems mouse, tissue culture, 3D human tissue culture and techniques molecular, biochemistry, genetic, histology, and genomics.
Postdoctoral research in the lab commonly involves close interactions both within the lab and with collaborating groups at the University of Pennsylvania.
Postdoctoral training includes participation in seminars and retreats of the Department of Dermatology and Institute of Regenerative Medicine.
A major goal of our lab is to mentor and train fellows for future careers in academics and industry.
To apply, please email a letter of interest and a CV that includes three references to Dr.
Please include a statement about your interest in our lab and your career goals and objectives.
Select publications include: Leung T.
The Journal of Clinical Investigation.
Curr Mol Med 15 2 :138-45.
Molecular Psychiatry 18 7 :740-2.
Neuroscience Research 71 3 :289-93.
Nature Immunology 9 1 :34-41.
Assistant Professor Department of Psychiatry and Behavioral Sciences Hollywood casino columbus ohio address Hopkins University School of Medicine E-mail: skano2 jhmi.
Baylor is a recognized world leader in islet transplantation research.
The team has numerous external grant awards including from the Juvenile Diabetes Research Foundation and the National Institutes of Health.
We average some 10 publications per year.
Strong problem solving skills, creative thinking and the ability to write grants will be a plus.
Financial support for this position is included.
Baylor Research Institute will assist the successful applicant in obtaining necessary visa.
The exciting work will be guided by multidisciplinary collaborations with top scientists in transplantation, immunology, autoimmunity, diabetes at Baylor Research Institute.
To apply please send your CV, a brief statement of research interests and contact information for three references.
E-mail : bashoon BSWHealth.
Cancer Biology University of Cincinnati College of Medicine Brain Tumor Center at UC Neuroscience Institute UC Cancer Inst.
A highly motivated postdoctoral scholar will work on NIH-funded research projects to study the neurobiology of energy homeostasis, motivated behavior, autonomic and blood pressure regulation relating to obesity, hypertension and eating disorders.
To accomplish this, a combination of cutting-edge tools will be employed, including in vivo Cre-loxP technology, optogenetics and chemogenetics, neuroanatomy, neurophysiology, biochemistry and molecular biology.
Applicants should have a Ph.
Prior working experience with animal models is highly desirable.
Preference will be given to those who have ex!
To Apply: Interested candidates should submit their current curriculum vitae, letter of interest, and contact information for 3 references to Dr.
Huxing Cui by e-mail at: huxing-cui uiowa.
Japanese communication is possible as PI speaks fluent Japanese language close to native level.
All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.
We are seeking a highly motivated early career Postdoctoral Researcher.
Our laboratory uses structural biology, biophysics, biochemistry and cell biology.
We study the actin cytoskeleton, and the linkage between the cytoskeleton, cellular membranes and signaling pathways.
The laboratory and shared facilities at UPenn offer state of the art instrumentation.
UPenn is the leading institution in the world in cytoskeleton research, offering a fantastic training environment and great opportunities for career development.
Philadelphia is an affordable and cosmopolitan city, located in the Boston-New York-Washington DC corridor along the east coast of the US.
We offer competitive salary and benefits, according to experience.
Please send your CV, a cover letter explaining your interest in our laboratory, and provide the names and contact information of three referees to: Dr.
We study the role of Wnt signaling during early development using Xenopus and zebrafish models.
Preference will be given to applicants who are highly motivated, have a good publication record and hold a recent PhD in a related area of study.
Applicants should email a copy of their CV, reprints of relevant publications and the contact information of three references to Dr.
Raymond Habas habas temple.
Robert Welner, PhD at the University of Alabama at Birmingham for studies of leukemia stem cell maintenance, and alteration to the microenvironment during leukemogenesis.
Our lab uses mouse models to decipher the gene regulatory network of cells within the leukemic microenvironment that inhibit normal hematopoiesis.
Additionally, we work with primary patient samples to translate these findings to human disease.
The candidate will take advantage of mouse genetics, epigenetics, molecular and cellular biology, and single cell technologies to achieve these goals.
Recent publication for reference: Cancer Cell 2015, 11;27 5 :671-81.
The Division of Hematology-Oncology is part of the NCI-funded Comprehensive Cancer Center, one of the nation's leading cancer research and treatment centers.
This position is seeking an energetic, research-oriented individual with a strong background in molecular or cellular biology, or immunology as well as experience in studying hematopoiesis will be preferred.
The candidate should be organized, self-motivated, and have good communication skills.
We aim to be a highly collaborative team, and the ability to work successfully with others is critical.
Please send cover letter, research interests, and curriculum vitae with the names of three references to: Rob Welner, PhD, Assistant Professor University of Alabama at Birmingham Department of Medicine, Division of Hematology-Oncology Email: rwelner uab.
Sanford Burnham Prebys SBP is known for its world-class capabilities in stem cell research and drug discovery technologies and is an NCI designated Cancer Center.
SBP is located on the scenic Torrey Pines Mesa and has collaborative ties to several adjacent world-class research institutions such as a the Salk Institute, Scripps and the University of California San Diego as well as several leading pharmaceutical companies.
The Deshpande lab is interested hollywood casino columbus ohio address cancer epigenetics with a core focus on hematological malignancies using mouse models.
The lab also has a strong interest in normal hematopoietic stem cell biology.
The candidate will be involved in the study of normal and cancerous stem cells using genomic, epigenomic and biochemical methods, high-throughput small molecule inhibitor screens and CRISPR-Cas9 mediated genome editing.
Requirements Highly motivated candidates with a recent Ph.
Basic knowledge of computational data analysis is a big plus but not a must.
We are seeking collaborative individuals who are detail oriented, with excellent communication and data organization skills.
Candidates must have a demonstrated ability to successfully spearhead a research project as evidenced by first author publications in reputable and high impact journals published or submitted.
Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for 3 letters of reference to Dr.
Ani Deshpande adeshpande SBPdiscovery.
Place of work The Institute of Human Genetics www.
Fully endowed with state-of-the-art scientific equipment, the IGH generates a stimulating and international research environment, for high-quality and intensive scientific life.
The working language is English.
The city is one of the most lively and concentrated areas for research scientists in France.
The team Our multinational team wishes hollywood casino columbus ohio address understand how DNA replication origins are recognized, and how their organization is coordinated with the cell fate.
Our model systems include cell cultures from both mouse and human cells, as well as in-vitro DNA replication systems from Xenopus eggs.
Recently, our laboratory unravelled how genetic and epigenetic features shape DNA replication origin recognition and organization.
The project is focused on functional aspects of metazoan DNA replication origins, using in-vivo cell systems as well as in-vitro cell systems to analyse the regulation of DNA replication and its associated factors.
Qualification We would be glad to receive applications from highly motivated scientists, able to work independently, with a solid background in nuclear metabolism and strong expertise in molecular biology.
The position is for at least two years.
Please submit a curriculum vitae and contact information of two referees to Marcel Méchali, Institute of Human Genetics, CNRS, 141 rue de la Cardonille, 34396 Montpellier, France.
Tel: +33 0 434 359 917; e-mail: mechali igh.
A Post Doctoral Fellow position is available in the laboratory of Dr.
The lab investigates gene regulation by non-coding RNAs by employing a combination of biochemistry, cell and molecular biological methods, and genome wide approaches.
Candidates with research interests in chromatin biology, epigenetics, and long non- coding RNAs are encouraged to apply.
Candidates should have a PhD or equivalent degree or should be close to obtaining their doctoral degree.
Interested individuals should apply by submitting a cover letter stating the reason for their interest in the position, a CV including a list of publications, and the names and contact information for at least 3 references to ksarma wistar.
The Wistar Institute is an independent biomedical research institute founded in 1892 and is world renowned for its research in cancers and vaccine development.
It is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus.
Both the Wistar Institute and the University of Pennsylvania provide resources to conduct cutting edge collaborative research, outstanding intellectual environments and state-of-the-art facilities.
We offer an excellent benefits package.
For more information about The Wistar Institute visit our website at www.
It is the policy of The Wistar Institute to provide equal employment opportunities to all individuals regardless of race, color, creed, religion, national origin, ancestry, sex, age, veteran status, disability, sexual orientation, gender identity, or on the basis of genetic information, or any other characteristic protected by federal, state, or local law, with respect to all terms and conditions of employment.
A postdoctoral position is available working in the laboratory of Hiroki Taniguchi Ph.
We are looking for highly motivated individuals who will enjoy the process to achieve a unique science and have a strong ambition to create trends of neural circuit research in the future.
The research focus of the MPFI is structure and function of neural circuits, the complex synaptic networks of the brain.
The MPFI has had a lot of exciting seminars presented by world-renowned researchers, and a close relationship with the Scripps Florida Institute and Florida Atlantic University on the same campus.
Research Topics Cortical inhibitory interneurons have many subtypes, each of which has a unique role in various functions of neural circuits.
Thus, elucidating mechanisms by which their diversity arises and functional role of subtypes in neural circuit operation is one of key missions in neuroscience.
We have taken advantage of mouse genetics, molecular biology, virology, and imaging techniques to understand fate specification, neural circuit development, and a role in higher-order brain functions, of cortical interneuron subtypes.
In this recruitment, we are interested in candidates who are eager to study one of these subjects.
Location Max Planck Florida Institute, Jupiter, Florida, USA.
Jupiter is located in south Florida and surrounded by a lot of nature.
There are many good school districts within the area.
It is warm throughout the year.
It must be good for family.
Qualification Applicants must have or be expected to receive a Ph.
Salary and benefits In accordance with MPFI regulations Start of employment As early as possible negotiable Application and required documents 1.
Complete CV including a publication list, experimental skills and contact information on 3 reference persons 2.
Description of current and previous research summary 1-2 page 3.
Description of the reason why you apply and what you want to do 1-2 page A PDF should be sent to Hiroki Taniguchi, Ph.
Contact prior to application is welcome.
D Chair, Immunology Graduate Program Associate Professor Department of Immunology University of Texas Southwestern Medical Center 6000 Harry Hines Blvd, NA7.
We are particularly interested in the pathogenesis and targeted therapy of lung cancer, mechanisms of resistance to targeted therapy, and how to overcome resistance to targeted therapy.
Applicants should hold a Ph.
Full applications including curriculum vitae and a list of three references should be submitted through chengpostdocapps gmail.
Our group studies how injured tissues heal, and in some cases, how injured tissues regenerate without a scar.
We have innovated new methods for studying these processes in mice and humans, and discovered cellular, molecular, and genetic mechanisms governing inflammation, wound healing, and tissue regeneration.
Based on our findings, we have several active clinical trials testing our conclusions in the clinic.
As a practicing dermatologist, I try to use clinical observations to drive basic science discovery.
An overarching goal of our work is to identify novel therapeutic strategies to improve healing with or without scars in humans.
We are seeking a qualified postdoctoral fellow with an interest in stem cells, inflammation, tissue regeneration, and regenerative medicine.
The fellow will design and perform experiments using a variety of model systems mouse, tissue culture, 3D human tissue culture and techniques molecular, biochemistry, genetic, histology, and genomics.
Postdoctoral research in the lab commonly involves close interactions both within the lab and with collaborating groups at the University of Pennsylvania.
Postdoctoral training includes participation in seminars and retreats of the Department of Dermatology and Institute of Regenerative Medicine.
A major goal of our lab is to mentor and train fellows for future careers in academics and industry.
To apply, please email a letter of interest and a CV that includes three references to Dr.
Please include a statement about your interest in our lab and your career goals and objectives.
Journal of the American Academy of Dermatology.
The Journal of Clinical Investigation.
A cellular and molecular biology laboratory in the Department of Medicine at Boston University School of Medicine is seeking to hire a post-doctoral research fellow.
Boston University School of Medicine and Boston University are premier research institutes drawing substantial amount of extramural and industry funding.
The Division of Nephrology is within the Department of Medicine, whose goal is to understand various aspects of renal diseases, their pathogenesis, effects on various organ systems and has been at the forefronts of developing novel pathogenic biomarker for glomerulonephritis and other vascular diseases.
One of the research focuses of the group is to characterize the pathogenesis of vascular disease in patients with chronic kidney disease.
Successful candidate will conduct research at the intersection of cellular biology, biochemistry, and analytical chemistry.
The candidate will work with a multidisciplinary team including clinical nephrologists, molecular and cellular biologists and proteomic experts and system biologists of Boston University and Boston University School of Medicine, thus the project is truly of translational in nature.
US citizens or green card holders are preferred for this position.
Self-motivation, dedication to work and enthusiasm to learn are must for this position and a person who can commit 2-5 years for a productive scientific career are encouraged to apply.
The position is available on immediate basis.
Interested applicants should contact Dr Vipul Chitalia, MD PhD, Assistant Prof of Medicine, Boston University School of Medicine, Boston.
We also use mammalian model systems e.
One must have basic training in molecular biology e.
Candidates must be able to work independently to develop their own research project, but also be willing to work as part of a larger group and be a great team player.
If you are interested in working with us, please send your Curriculum Vitae, 1-2 page document that describes your research interests and future goals, and contact information for three 3 references to yamamoto bcm.
The position will remain open until filled.
Project Title: The role of caveolin-1 in mediating cardiovascular pathophysiology.
Position Type: Postdoctoral Position and Visiting Researcher at an Academic Institution My laboratory is looking for a post-doctoral fellow 2 year or more or visiting Researcher 1 year minimum to conduct both in vitro and in vivo research experiments focused on the signal transduction mechanism of vascular disease development via caveolin-1 using primary culture and mouse models of atherosclerosis, hypertension and aortic aneurysm.
Cutting-edge cell biological and biochemical approaches, genetic mouse models, and human tissue specimens will be employed during the training period.
Applicants must have a Ph.
Two positions are currently available with partial financial support for the fellow starting from 2nd year or no financial support a 1 year Visiting Researcher.
Familiarity with at least one of the followings: cell biology, biochemistry, mouse models, and surgical skills.
Publication record in biomedical journals.
Victor Rizzo, PhD Professor of Medicine Temple University School of Medicine Department of Anatomy and Cell Biology Independence Blue Cross Cardiovascular Research Center 3500 N.
Our primary goal is to understand how transcriptional and post-transcriptional regulatory mechanisms work in concert to give rise to circadian protein expression that ultimately drive a wide range of rhythmic biochemistry, physiology, and behavior.
The successful candidate will elucidate the complex contribution of poly A tail to regulating and fine-tuning circadian gene expression using multiple-disciplinary approaches including but not limited to transcriptome, cellular and biochemical, real-time imaging studies.
The position is for one-year with annual contract renewal pending performance.
Open immediately, start date negotiable.
Assistant Professor Biocomplexity Institute Department of Biological Sciences Virginia Tech Email: skojima vt.
Position is for 2 years.
Postdoctoral Position Defining Molecular Mechanisms of Cell Signaling and Their Roles in Cancer A POSTDOCTORAL position is available in the laboratory of Dr.
The Princess Margaret Cancer Centre is among the top 5 Cancer Research Centres in the world.
The position is available for a creative post-doctoral candidate with demonstrated expertise in cell signaling and cancer mechanisms.
Biochemistry, cellular and molecular biology, mouse models and human tumors are used for our studies.
Recently graduated and highly motivated PhD candidates with strong background in cell signaling and cancer mechanisms are encouraged to apply.
Interested applicants should submit their C.
Please note that only qualified candidates will be contacted.
A postdoctoral position is available at the Gene Regulation Section, Laboratory of Molecular Biology, Center for Cancer Research, NCI, to study the molecular genetics of thyroid cancer using cell-based studies, xenograft and mouse models.
In particular, the possible involvement of cancer initiation cells and the collaborative cross talks of oncogenic signaling of mutant thyroid hormone receptors with other cellular signaling pathways e.
Candidates must have a Ph.
Applicants should submit a complete CV with a photo and a list of publications, a statement of interests and career goals, a copy of Ph.
The NIH is dedicated to building a diverse community in its traini!
Sheue-yann Cheng, e-mail: Chengs mail.
The laboratory headed by Dr.
Ajay Goel, PhD focuses on understanding the interplay between genetic, epigenetic and alterations in noncoding RNAs in gastrointestinal cancers.
We are a multidisciplinary research group, undertaking a number of collaborative projects involving Baylor Research Institute and large international consortia.
Research Description: This position involves studies surrounding work in the field of epigenetics and noncoding RNA research.
Job Description: An ideal candidate should have a strong background hollywood casino columbus ohio address molecular biology, and relevant experience in cancer genetics and epigenetics.
Knowledge and experience with various bioinformatics and biostatistical analysis tools will be highly preferred.
The position will continue to focus on developing the skills necessary to obtain grants and scientific publications and become an independent Investigator.
Radiation Safety, Animal Handling, etc.
Attends and participates in weekly Lab meetings and other venues for sharing and discussing ideas and results of the ongoing research projects.
Prospective candidates should be highly motivated, enthusiastic about science, with an ability to think creatively and independently.
Candidate should demonstrate a strong track record of publication, have good organizational, written, and oral communication skills, and be able to work independently and in a team environment.
To Apply: The position is available initially for 2-3 years, with potential for extension.
Salary is commensurate with experience.
Interested candidates should submit a CV and cover letter summarizing your Qualifications, Research Interests and Career Goals, and describe your specific interest in our lab.
Include the names and contact information of 3 references and send via email to: Ajay Goel, Ph.
Investigator Director, Center for Gastrointestinal Cancer Research Director, Center for Epigenetics, Cancer Prevention and Cancer Genomics Baylor Research Institute and Charles A Sammons Cancer Center Baylor University Medical Center 3500 Gaston Avenue, Suite H-250 Dallas, TX 75246 E-mail: ajay.
We are seeking to appoint an outstanding individual with Ph.
We recently identified 19 uncharacterized kinetochore proteins named KKT1—19 in Trypanosoma brucei and discovered that they constitute unconventional kinetochores specific to kinetoplastids, a group of evolutionarily distant eukaryotes Akiyoshi and Gull, Cell 2014.
We are currently characterizing these KKT proteins using various techniques including bioinformatics, super-resolution microscopy, biochemistry, biophysics, and structural biology.
This full-time post is funded by the Wellcome Trust and Royal Society for up to two years in the first instance.
This position is graded on the University's Grade 7 scale, for which the salary range is £30,434 -£37,394 per annum.
Tanaka is an Associate Professor at the Department of Pathology, University of Oklahoma School of Medicine, and Stephenson Cancer Center, Oklahoma.
Projects will employ a basic biochemical, molecular biological approaches, as well as translational and clinical researches on understanding: 1.
How vascular inflammation supports hematogenous metastasis.
Previously, the lab has demonstrated that vascular inflammation enhances a chance of hematogenous metastasis and developed the prevention therapy to inhibit hematogenous metastasis.
What molecular signatures in circulating tumor cells contributes hematogenous metastasis.
How differential tumor microenvironment impact on therapeutic outcome.
Highly motivated individual Ph.
Required expertise includes the following skills, but not limited to: cell culture, molecular and cell biology techniques, mouse handling, protein evaluation immunoblotting and histologyconfocal microscopy, quantitative image analysis, mouse model of cancer, and flow cytometry.
Appointee will be expected to participate in research data collection and documentation within relevant guidelines and protocols; developing and evaluating new research techniques and procedures; publishing results in scientific journals; participating research meetings.
The ideal candidate should be able to take a lead role on a project and report to the PI.
Salary is commensurate with experience.
To apply, send a letter indicating your research interests and experience, a curriculum vitae, and the names of three individuals who may be contacted for references to: Takemi Tanaka, Ph.
Nima Sharifi at the Cleveland Clinic Lerner Research Institute in the Department of Cancer Biology.
Please see our recent papers in Nature and Cell and our laboratory website for further information.
My preference is an energetic critical thinker and experimenter.
I will appreciate any inquiry in Japanese or English at hyokota iupui.
This is because DNA, the blueprint of life, is an active large molecule with many active chemical moieties that allow it to receive numerous modifications.
Such modification will result in the change of the double helix structure, which then hollywood casino columbus ohio address to abnormal or even lethal endpoint on the affected cell, for instance, the rising of cancer, premature aging and neuro-degenerative diseases.
Fortunately, it turns out that evolution has overlaid elegant signaling pathways to sense the presence and initiate the repair of DNA damage that can arise both through exposure to environmental stress such as the UV light and through cellular activities such as free radical species.
These signaling pathways are called DNA damage response.
We use pharmacological, biochemical, structural and genetic tools to understand molecular mechanisms underlying the DNA damage response, and translating that knowledge into therapeutic strategies against human cancers.
Strong background in biochemistry Western blotting, immunofluorescence, immunoprecipitation, etcmolecular PCR, cloning and vector generation and cellular cell culture, transfection, and so on biology is required.
Interested applicants should forward their CV and a list of three references through email to: Dr.
Clint Robbins and Myron Cybulsky at the Toronto General Research Institute and University of Toronto.
The postdoctoral fellow will study the mechanisms that maintain tissue resident macrophage populations in health and disease.
Requirements: Candidates will have a Ph.
Experience in macrophage biology is preferred, but not necessary.
The successful candidate must be highly motivated and independent, possess good verbal and written communications skills, and have a good track record of scientific accomplishments including publications in peer-reviewed journals.
Preference will be given to candidates who attained their postgraduate degree within the last 2 years.
Applicants should respond by email with a curriculum vitae and brief description of research interests to Dr.
Nghiem's Laboratory University of Washington Dermatology A position for a postdoctoral fellow is available in the laboratory of Dr.
These studies will be co-led with Masaoki Kawasumi, MD, PhD Acting Assistant Professor.
The goal of these NIH-funded studies is to elucidate molecular mechanisms by which cells sense UV-induced DNA lesions CPD and 6-4PP and activate biological processes such as ATR-Chk1 checkpoint signaling, DNA repair, and mutagenic translesion synthesis and to dissect the molecular mechanisms by which caffeine prevents multiple types of skin cancers.
Our approaches include cell culture, flow cytometry, DNA replication track analysis, Western blot analysis, chromatin immunoprecipitation ChIPproteomics, next-generation!
Applicants should have good written and oral communication skills.
Salary will be commensurate with experience and based on NIH and the University of Washington guidelines.
Applicants should submit a letter of interest, CV, and the names of three potential references electronically to Dr.
Please visit our lab website at www.
Nghiem's Laboratory 850 Republican St, Rm 242 Seattle, WA 98109-4714 Phone: 206-221-4594 FAX: 206-221-4364 E-mail: kawasumi uw.
Novel areas in the lab include: i Epigenetic and molecular programs of MMC9 development and!
Advanced immunologic approaches, animal models, and defined human tissue biopsies are employed in these studies.
The Division is a high-energy, dynamic, and interactive environment that is interested in recruiting self-motivated individuals with the drive to succeed and the desire to be competitive at the international level.
Candidates with a strong background in molecular biology and immunology are encouraged to apply.
Salary is competitive with an attractive benefits package that includes family health insurance, etc.
For consideration, please send CV and contact information to Dr.
Project Title: Role of inflammatory derived proteases in cardiac repair.
Position Type: Postdoctoral Position and Visiting Researcher at an Academic Institution My laboratory is looking for a post-doctoral fellow or visiting Researcher 2 year or more to conduct both in vitro and in vivo research experiments focused on understanding the role of inflammatory serine proteases in cardiac repair after myocardial infarction.
Cutting-edge cell biological and biochemical approaches, genetic mouse models, and human tissue specimens will be employed during the training period.
Applicants must have a Ph.
The position is currently available with partial in year 1 and full in year 2 financial support for the fellow.
Highly motivated applicants with strong background in immunology or molecular biology preferred.
Familiarity with ELISA or FACS technique is desired.
Publication record in biomedical journals desired.
Abdelkarim Sabri, PhD Professor of Medicine Temple University School of Medicine Department of Physiology Independence Blue Cross Cardiovascular Research Center 3500 N.
Chan School of Public Health is looking for an outstanding postdoctoral fellow.
Emerging studies indicate that metabolic reprogramming critically controls macrophage activation, and a variety of projects are available in the lab addressing various aspects of such control, including the metabolic basis of Nlrp3 inflammasome activation; metabolic crosstalk between tumor associated macrophages and tumor cells; and metabolic influences on chromatin-mediated control of macrophage activation and memory.
Candidates should be skilled in cell biology, molecular biology, and basic mouse work.
Candidates must have a Ph.
Please submit application, including a cover letter, CV and names and contact information of at least 3 references to: Tiffany Horng, Ph.
Associate Professor Department of Genetics and Complex Diseases Harvard School of Public Health 655 Huntington Ave, II-115 Boston, MA 02115 thorng hsph.
Chan School of Public Health, Brigham and Women's Hospital, and Harvard Medical School, in Boston, MA, USA.
Salary can be offered if a candidate has specific skills and expertise.
A position may be a research scientist or postdoctoral fellow.
Candidates in other areas can be considered; other areas include epidemiology, biostatistics, molecular biology, immunology, and clinical medicine.
Candidates with funding support will be highly considered, but candidates without funding will also be considered.
My laboratory is The "Molecular Pathological Epidemiology" MPE Laboratory, which is a very unique, interdisciplinary multi-institutional laboratory.
I established an integrative science of MPE Ogino et al.
J Natl Cancer Inst 2010; Ogino et al.
Nat Rev Clin Oncol 2011; Field et al.
JAMA 2013; etcand founded the International MPE Meeting Series.
I recently hosted The Second International Molecular Pathological Epidemiology MPE Meeting on Dec 4-5, 2014, and it concluded as a resounding success.
Indeed, I have been making history of MPE.
In terms of disease areas, my lab has been working on colorectal cancer, pancreatic cancer, and gastrointestinal neuroendocrine tumors.
We have been utilizing resources of the Nurses' Health Study followi!
For more information, please visit these links.
Please pass this information to anyone who may be interested.
Please pardon me if I cannot reply to you because of too many responses or inquiries.
Selected original publications: R Nishihara et al.
NEJM 2013; X Liao et al.
NEJM 2012; AT Chan et al.
NEJM 2007; E Barry et al.
Nature 2013; R Straussman et al.
Nature 2012; M Giannakis et al.
Nat Genet 2014; K Mima et al.
JAMA Oncol 2015; R Nishihara et al.
JAMA 2013; T Morikawa et al.
JAMA 2011; AT Chan et al.
JAMA 2009; S Fink et al.
Sci Transl Med 2014; ZR Qian et al.
J Clin Oncol 2013; A Kostic et al.
Genome Res 2012; M Song et al.
JNCI 2015; K Inamura et al.
JNCI 2014; P Lochhead et al.
JNCI 2013; S Ogino et al.
JNCI 2013; A Kuchiba et al.
JNCI 2012; M Song et al.
Gut 2015; M Yamauchi et al.
Gut 2012; K Mima et al.
Cancer Immunol Res 2015; etc.
JNCI 2010; S Ogino et al.
Nat Rev Clin Oncol 2011; A Field et al.
Professor Department of Pharmacology and Neurology Boston University School of Medicine, Boston, MA 02118, USA Email: tikezu{at}bu.
Applicants should hold a Ph.
Full applications including curriculum vitae and a list of three references should be submitted through chengpostdocapps gmail.
Ya-Ming Hou at Thomas Jefferson University, Sidney Kimmel Medical College.
The laboratory studies molecular and cellular mechanisms that protect against neurodegeneration associated with mitochondrial diseases.
Current topics include systematic analysis of tRNA biosynthesis, maturation, and translational activity in mitochondria and in disease.
For more information, please see the following publications and websites.
Experience in fluorescence microscopy, mammalian cell culture, molecular biology, biochemistry, protein enzymology, nucleic acid research, and mitochondrial research is preferred.
Professor, Department of Biochemistry and Molecular Biology Thomas Jefferson University Sidney Kimmel Medical College 233 South 10th Street, BLSB 220 Philadelphia, PA 19107 Email: ya-ming.
Computational Medicine Center Department of Biochemistry and Molecular Biology Thomas Jefferson University 1020 Locust Street, Jefferson Alumni Hall m-77, Philadelphia, PA 19107, USA Tel: +1-215-503-8648 Email: Yohei.
Proc Natl Acad Sci, USA, 112: E3816-E3825, 2015.
RNA Biol 12: 501-508, 2015.
RNA Biol 12: 375-380, 2015.
Nucleic Acids Res 43: e77, 2015.
Proc Natl Acad Sci, USA 112: E1106-1115, 2015.
You can see the detail information in the above sites.
Please submit your CV into the above two positions to select the suitable position via equal opportunity.
Expected at least above 2 yrs contract total 4 yrs project.
Expected collaboration with Vanderbilt Cancer Center.
J visa candidates will be expected to reduce salary because of tax exemption.
Good candidates will be supported to live enough in Nashville, TN, USA.
Further information, send email deokson gmail.
Requirements include a Ph.
It is preferred that the candidate has experience with analysis of animal models including lineage tracing in transgenic mice as well as familiarity with FACS and at least 2-3 years of research experience after graduation.
The position comes with opportunities for advancement to Senior Research Associate and Assistant Research Professor level.
Candidates should submit a cover letter including a description of their research interests, curriculum vitae, and the names and contact information of three references.
Applications should be e-mailed as Word or PDF attachments to Dr.
Per Flodby at flodby usc.
Postdoctoral Fellow Position One postdoctoral fellow position is available immediately in the laboratory of Dr.
Haijiang Cai in the Department of Neuroscience at the University of Arizona.
The research of the lab focuses on the neural circuits and mouse behaviors, using optogenetics, pharmacogenetics, molecular and electrophysiological tools.
To apply, please send a letter of interest, Currivulum Vitae, and contact information of two to three references to haijiangcai email.
We have combined mouse genetics transgenic and knockout micecell biology and genomic analysis to tackle these important issues.
We are located at the vibrant UCSF Mission Bay campus, which provides an exceptionally stimulating scientific environment and an incredible opportunity for collaboration.
Please send CV, brief statement of research interests and names of three references to: Dr.
Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco 555 Mission Bay Blvd South, Rm 252F San Francisco, CA 94158 USA E-mail: pao-tien.
Postdoctoral position available to study the molecular mechanisms of cell-cell interactions in mammalian development and disease using mouse as a model system.
We focus on the Hedgehog Hh signaling pathway, which is critical for many aspects of embryonic development, and aberrant regulation of the pathway results in a wide variety of congenital defects and cancers.
The two main areas of research interest are: 1 The molecular characterization of the Hedgehog signaling pathway.
We wish to understand the molecular mechanisms by which the Hh signal is transduced; 2 The roles of Hh signaling in postnatal physiology and homeostasis such as stem cell maintenance and cancer formation.
In all of our studies, a combination of mouse genetics transgenic and knockout micecell biology and biochemistry are employed.
We are located at the vibrant UCSF Mission Bay campus, which provides an exceptionally stimulating scientific environment and an incredible opportunity for collaboration.
Please send CV, brief statement of research interests and names of three references to: Dr.
Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco 555 Mission Bay Blvd South, Rm 252F San Francisco, CA 94158 USA E-mail: pao-tien.
Mutsuko Minata mmtododon1 gmail.
Infectivity-selective oncolytic adenovirus developed by high-throughput screening of adenovirus-formatted library.
Our lab focuses on Translational research and Cellular Immunotherapy.
Academic activities such as manuscript writing, conference attendance and other scholarly activities are included.
Strong support for career development will be provided.
The successful applicant will hold a Ph.
Knowledge in immune assays, FACS, cell culture, PCR, mice handling, cell transfections or molecular biology are points considered for evaluation.
Hands-on knowledge in Bioinformatics and microarray analysis software will be considered a plus.
Interested candidates please send a CV, a brief personal statement and references for contact to: Richard Koya richard.
Associate Professor Veterans Affairs and University of California, San Francisco Yuichiro.
Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells.
Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma.
DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells.
Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men.
Long Non-coding RNA HOTAIR Is Targeted and Regulated by miR-141 in Human Cancer Cells.
Hrk mediates 2-methoxyestradiol-induced mitochondrial apoptotic signaling in prostate cancer cells.
Applications are now being accepted for the Iowa Muscular Dystrophy Cooperative Research Center Postdoctoral Fellowship in my laboratory.
Applicants should have a Ph.
The Iowa Wellstone Center is particularly interested in training the next generation of scientists in translational research on muscular dystrophy.
Typically, a fellow in this position does full-time research in my laboratory, and also has the opportunity to observe patient care in the muscular dystrophy clinic, under the supervision of pediatric neurologist Dr.
Fellows present their findings at lab meetings and monthly Neuropathology Disease Conferences.
In addition, they attend the annual, face-to-face Wellstone meeting with scientists and physicians across the country who are supported by Wellstone Center Grants.
The University of Iowa Wellstone Center offers outstanding state-of-the-art facilities to conduct molecular biology and cellular biology studies.
Fellows will receive a competitive starting salary with excellent benefits for at least three years.
For prompt consideration send or email letter of application, curriculum vitae, and names of three references to: Dr.
Campbell Howard Hughes Medical Institute University of Iowa Carver College of Medicine 4294 Carver Biomedical Research Building 285 Newton Road Iowa City, IA 52242 Email: kevin-campbell uiowa.
Applicants should have a Ph.
The goal of this research is to generate new knowledge regarding the glycosylation of dystroglycan, to identify and define disease mechanisms that cause muscular dystrophy and to develop therapeutic strategies for these diseases.
I will be able to provide a competitive starting salary with excellent benefits for at least three years.
The University of Iowa, Howard Hughes Medical Institute and the Muscular Dystrophy Cooperative Research Center offer outstanding state-of-the-art facilities to conduct molecular and cellular biology studies.
For prompt consideration send or email letter of application, curriculum vitae, and names of three references to: Dr.
Campbell Howard Hughes Medical Institute University of Iowa Carver College of Medicine 4294 Carver Biomedical Research Building 285 Newton Road Iowa City, IA 52242 Email: kevin-campbell uiowa.
We have combined mouse genetics transgenic and knockout micecell biology and genomic analysis to tackle these important issues.
We are located at the vibrant UCSF Mission Bay campus, which provides an exceptionally stimulating scientific environment and an incredible opportunity for collaboration.
Please send CV, brief statement of research interests and names of three references to: Dr.
Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco 555 Mission Bay Blvd South, Rm 252F San Francisco, CA 94158 USA E-mail: pao-tien.
Postdoctoral position available to study the molecular mechanisms of cell-cell interactions in mammalian development and disease using mouse as a model system.
We focus on the Hedgehog Hh signaling pathway, which is critical for many aspects of embryonic development, and aberrant regulation of the pathway results in a wide variety of congenital defects and cancers.
The two main areas of research interest are: 1 The molecular characterization of the Hedgehog signaling pathway.
We wish to understand the molecular mechanisms by which the Hh signal is transduced; 2 The roles of Hh signaling in postnatal physiology and homeostasis such as stem cell maintenance and cancer formation.
In all of our studies, a combination of mouse genetics transgenic and knockout micecell biology and biochemistry are employed.
We are located at the vibrant UCSF Mission Bay campus, which provides an exceptionally stimulating scientific environment and an incredible opportunity for collaboration.
Please send CV, brief statement of research interests and names of three references to: Dr.
Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco 555 Mission Bay Blvd South, Rm 252F San Francisco, CA 94158 USA E-mail: pao-tien.
Postdoctoral fellows — electrophysiology and calcium imaging in behaving rodents We invite applications for two postdoctoral positions in the laboratory of Dr.
Ayumu Tashiro in Warwick-NTU Neuroscience research program, Nanyang Technological University, Singapore.
Our work focuses on the function of hippocampal circuitry through a multi-disciplinary approach combining virus-mediated genetic manipulation, optogenetics, behavioral analysis and unit recording techniques in behaving rodents.
Successful candidates will examine the mechanisms underlying place-cell activity in the rodent hippocampus, using a combination of virus-mediated genetic manipulation and unit recording Kitanishi et al.
To apply for the positions, please send your C.
Coordination of entorhinal-hippocampal ensemble activity during associative learning.
Rangel LM, Eichenbaum H.
Functional diversity along the transverse axis of hippocampal area CA1.
Parallel mitral and tufted cell pathways route distinct odor information to different targets in the olfactory cortex.
Research Associate Kavli Institute for Systems Neuroscience, Norwegian University of Science and Technology NTNU E-mail: igarashi.
Areas of interests include craniofacial morphogenesis, skeletal development, mesenchymal stem cell, neural crest and neural development, congenital deformities, cancer and metastasis.
The Zheng lab studies the activity and function of post-transcriptional gene regulation in the nervous system.
The position offers an amazing opportunity to continue training in neuroscience and RNA biology with an emphasis on cell and molecular biology, imaging, stem cells, mouse genetics, biochemistry, genomics, next generation sequencing and informatics approaches.
Strong background in RNA biology, developmental neurobiology, and mouse genetics is highly preferred.
Salary is commensurate upon experience and qualifications.
University of California Riverside has a vibrant research environment and is the fastest growing campus of UC.
Particular strengths on the campus include neurodevelopmental disorders, glial-neuronal interactions, genetics, epigenetics, genomics, bioinformatics, integrative immunology, cancer biology, microRNAs, vector biology, bioengineering and nanotechnology, and synthetic and analytical chemistry.
The scientific community is highly interactive, providing many opportunities for collaborations.
Our lab is fully equipped with modern instruments for neurogenetics research and is housed in a research building with state-of-the-art facility that was opened in 2011.
Riverside is a wonderful place to live, providing ample cultural and entertainment opportunities in a safe and comfortable community with very affordable housing and living expenses.
Riverside is about an hour away from ski slopes, surfing, or hiking in mountain or desert environments, and housing in the area is very affordable.
The city offers all the cultural advantages of any U.
The campus is also located in a prime position to take advantage of the other universities, research institutes, and biotech industries present in Southern California.
Please send CV, a description of research experience and interests, representative publications, and two or three references with contact information to sika.
We are especially interested in those who are energetic and highly motivated for career advancement.
Please arrange recommendation letters sent separately to sika.
A postdoctoral fellowship position s supported by NIDDK, CCHMC Academic Research Council and Burroughs Wellcome Fund are available in the laboratory of Dr.
Our research program focuses on the role of immune response in inflammation and metabolism.
Recently we have illustrated the first evidence for a critical role for IL-17RA signaling in driving NAFLD progression, as well as the first report of a role for microbe-driven IL-17 production in exacerbating hepatocellular damage in NAFLD Harley IT et.
Current studies are focused on defining the cellular and molecular mechanisms underlying the regulation of NAFLD pathogenesis by the IL-17 axis.
Current studies are focused on defining the cellular and molecular mechanisms underlying the ability to thermoneutral housing to modulate, immune responses, intestinal microbiome, obesity and NAFLD pathogenesis through regulation of transcriptional networks.
Of note, current projects are directly associated with translational research endeavors with a focus on an in depth analysis of the interplay between immune responses, obesity-associated sequelae and the outcomes of bariatric surgery in adolescents.
The position will provide a unique exposure to the use of animal models of obesity and obesity-associated sequelae and validation of the relevance of such findings in obese humans.
Further, the fellowship will encompass a multidisciplinary training in immunology, metabolism, molecular and cellular biology, and transcriptional networks.
Candidates must have proficiency in verbal and written English.
Candidates with an interest in the position should send their CV and contact information for 3 references to: senad.
The Nakai lab studies adeno-associated virus AAV and its application for gene therapy using in vitro tissue culture models and in vivo models including mice, cats and non-human primates.
In particular, the Nakai lab takes non-traditional multi-disciplinary approaches to study AAV viral proteins and virus-host interactions using the high-throughput next-generation sequencing NGS technology, barcoding, computer simulation and modeling, bioinformatics and biostatistics in addition to the traditional low-throughput structural and functional biology-based approaches, in collaboration with experts in each relevant field.
In addition, the Nakai lab studies novel functions of assembly activating protein AAPa newly disco!
Ultimately, the lab will develop the next generation gene delivery vector systems that are more ideal for human gene therapy based on much deeper understanding of AAV than ever.
By applying the new technologies that have been and will be developed in his lab, the Nakai lab tries to establish new approaches to treat diseases in the central nervous system CNSdiabetes and genetic diseases and control reproduction in collaboration with investigators across and outside the university.
In addition, the Nakai lab has had strong passion for addressing any unanswered questions in fundamental biological processes not directly relevant to AAV or gene therapy.
Nima Sharifi at the Cleveland Clinic Lerner Research Institute in the Department of Cancer Biology.
Our laboratory is focused on molecular mechanisms of androgen synthesis and androgen receptor AR gain-of-function that lead to resistance to androgen deprivation therapy and the translational relevance thereof.
Areas of interest in this laboratory include: 1 Metabolic and genetic changes required for androgen synthesis 2 Clinical validation in patients and clinical trials utilizing innovative approaches 3 Animal models of advanced prostate cancer for translational and therapeutic studies 4 Identifying targets for the development of new pharmacologic therapies We recently discovered that abiraterone, an FDA-approved drug, works by conversion to a more active steroidal metabolite Li, et al.
We are currently working toward defining the relationship between metabolite generation and treatment response in patients with prostate cancer and identifying new chemical entities that are determinants of treatment response.
We also discovered the first example of a gain-of-function in a steroid-synthesizing enzyme that enables prostate cancer resistance to hormonal therapy Chang, et al.
We are pursuing similar mechanisms and developing new treatment modalities based on these discoveries.
We previously discovered that prostate cancer becomes resistant to hormonal therapy by the synthesis of dihydrotestosterone through a pathway that circumvents testosterone, instead requiring 5α-androstanedione, a previously underappreciated intermediate metabolite.
This metabolic pathway occurs commonly in all models and patient tumors tested Chang, et al.
Proc Natl Acad Sci USA.
Our unprecedented approach to the identification of metabolic pathways in tumors from patients redefines the fundamental mechanism that drives the progression of resistant tumors.
This work was featured as a Research Highlight in Nature Reviews Urology Nat Rev Urol.
The position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development and clinical trials.
This research program is supported by the Howard Hughes Medical Institute, the American Cancer Society, the Prostate Cancer Foundation, the Department of Defense Prostate Cancer Research Program and the National Institutes of Health.
Candidates must have proficiency in verbal and written English.
Candidates with an interest in the position should send their CV and contact information for 3 references to: Nima Sharifi, M.
Kendrick Family Chair for Prostate Cancer Research sharifn ccf.
By using viral oncoproteins as a probe, we will investigate host translational regulation pathways involved in tumorigenesis.
A successful candidate will gain experience in performing gene expression analysis, cell culture-based transformation assays, and polysome fractionation assays.
The work will require experience in cell culture, microscopy, transfections, and viral gene transductions.
Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS 2011 Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator.
J Clin Invest 121: 3623-3634.
Shuda M, Velasquez C, Cheng E, Cordek DG, Kwun HJ, et al.
Proc Natl Acad Sci U S A.
Qualifications: A successful candidate must have a PhD or an equivalent degree in molecular biology, biochemistry, or related field with experience in cell biology and virology.
Other preferred qualifications include research experience in cellular translational regulation research, cancer virology, and cancer biology.
The selected candidate is expected to commence the appointment in Summer 2015.
How To Apply: If interested, please send letter of interest, CV, and names of three references by e-mail to: Dr.
Research projects are concerned with the following topics: Knockout and transgenic mice, pathogenesis and experimental therapeutics of complement-mediated diseases.
Candidates with the following training and experience are encouraged to apply: immunology, molecular biology, recombinant protein expression, antibody production and engineering, knockout and transgenic mice, mouse models of inflammatory and autoimmune diseases.
Please contact Dr Wenchao Song, Professor of Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
The influence of light on temperature preference in Drosophila.
Design and analysis of temperature preference rhythm in Drosophila.
Temperature integration at the AC thermosensory neurons in Drosophila.
Circadian rhythm of temperature preference and its neural control in Drosophila.
An internal thermal sensor controlling temperature preference in Drosophila.
Nature, 2008 Jul 10;454 7201 :217-20.
Assistant Professor Visual Systems Group Division of Pediatric Ophthalmology Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue, ML 7003 Cincinnati, OH, 45229 Office: R2.
The work involves molecular and cellular basis of embryo development, implantation, parturition as well as endometrial cancers utilizing transgenic and conditional knockout mouse models.
The program is looking for independent, energetic and highly motivated individuals who will be engaged in full-time research.
Speaking and writing skills in English language are highly desirable.
Salaries will be in accordance with NIH postdoctoral pay scale.
Masato Akutsu akutsu em.
Xiang Zhou xzhousph umich.
Research in the Zhou lab focuses on the development of statistical methods and computational tools for the analysis of large-scale and high-dimensional biological data from genetic association studies and high-throughput functional genomic sequencing studies.
Applicants should have, or be studying for, a PhD in statistics, biostatistics, computer science, bioinformatics, computational biology, or related quantitative discipline.
A strong computational background is required.
Applicants should send a CV, a short research statement, and names of three referees to xzhousph umich.
Review of applications will begin immediately, and continue until the positions are filled.
Xiang Zhou POSTDOCTORAL POSITIONS IN NEUROSCIENCE with specialization in Brain Vascular Biology The Department of Physiology of the Yong Loo Lin School of Medicine at National University of Singapore has immediate opening for postdoctoral positions in Neuroscience, with specialization in Brain Vascular Biology.
As part of a University-wide initiative on mechanisms of neuronal and synaptic injury in ageing and neurodegenerative diseases under the direction of Profs.
Carlos Ibanez and Edward Koo, we are seeking talented and enthusiastic individuals to join our laboratories for postgraduate training.
Under the direction of Drs.
Carlos Ibanez and Edward Koo, this project will focus on studies of the role of BDNF signaling in physiological and injury responses of cellular elements of the brain vascular system.
More information about these laboratories can be found at medicine.
This is an exciting opportunity for individuals who have received a doctoral degree within the past five years and with a strong background in vascular biology or cellular neurobiology to receive further training in basic and translational studies in neurodegenerative diseases.
Requirements: - Doctoral degree PhD in biological sciences - Experience on mouse models - Experience on vascular biology studies is preferred - Able to work independently with precision and possess good organizational skills Our labs are located on the Medical School campus of the National University of Singapore.

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